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Previous Volume 349:2362-2363 December 11, 2003 Number 24 Next

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To the Editor: Lu et al. (Sept. 18 issue)¹ report human immunodeficiency virus (HIV) infection presenting as monoclonal gammopathy of undetermined significance (MGUS) in a 46-year-old man and argue that young patients with MGUS should be screened for HIV infection. We believe that undue emphasis was placed on the presence of MGUS in this patient. Critically, the history of invasive, recurrent pneumococcal infection, a well-established clinical feature of HIV infection, should have sufficed to alert the clinicians to the possibility of HIV infection.² Furthermore, it would have been interesting to know his lymphocyte count during convalescence, since patients with recurrent . . . [Full Text of this Article]

Related Letters:

HIV Infection Masquerading as Monoclonal Gammopathy of Undetermined Significance
Lu C. M., Dezube B. J., Pantanowitz L.
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N Engl J Med 2003; 349:1192-1193, Sep 18, 2003. Correspondence

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