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Correspondence
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Volume 349:2469-2470 December 18, 2003 Number 25
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Estimated Timing of the Last Common Ancestor of the SARS Coronavirus

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To the Editor: Using the viral sequences derived from clinical specimens collected in Hong Kong between February and April 2003 from 139 patients with the severe acute respiratory syndrome (SARS),1 we attempted to estimate the timing of the last common ancestor of the coronavirus associated with the recent outbreaks of SARS. We previously reported the results of phylogenetic analysis, using the same set of spike-gene sequences as that in the SARS-associated coronavirus (SARS-CoV) isolated during the early phase of the outbreak (February to April) in Hong Kong and southern China, together with those available in the public data base.1

Assuming . . . [Full Text of this Article]



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