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RETROSPECTIVE Previous Volume 349:521-522 August 7, 2003 Number 6 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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Eighteen years ago, the Journal published two observational studies^1,2 of the relations between postmenopausal hormone-replacement therapy and cardiovascular diseases. One found that women who used such therapy had about half the risk that nonusers had; the other found that they had almost twice the risk. In each study, the relative risk was statistically different from a relative risk of 1.0, or no effect. These results seemed to be in serious conflict, although each study taken alone looked sound. In an accompanying editorial,³ I noted differences in the drugs used, the groups of patients studied, the outcomes ascertained, and other matters, . . . [Full Text of this Article]

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From the University of Chicago, Chicago.

Related Letters:

Hormone Therapy and Cardiovascular Disease
Kannel W. B., Levy D., Sullivan J. L., Bailar J. C. III
Extract | Full Text | PDF  
N Engl J Med 2003; 349:2075-2076, Nov 20, 2003. Correspondence

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