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On routine prenatal ultrasonography, the cavum septum pellucidum was absent and a possible posterior fossa malformation was noted in a 31-week male fetus with a normal karyotype. A magnetic resonance imaging (MRI) study demonstrated the absence of most of the corpus callosum (midline sagittal image, Panel A), except for a small component of the anterior body (arrow). A coronal image (Panel B) shows the classic contour of nonconverging lateral ventricles (the asterisk indicates the third ventricle). The remainder of the brain, including the posterior fossa, appeared normal.
Dysgenesis of the corpus callosum is a relatively frequent cerebral malformation. It is . . . [Full Text of this Article] |
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