To the Editor: Erythromelalgia is a rare disease of unknowncause, characterized by redness of the skin, increased temperature,and pain in the extremities. Erythromelalgia is often primary,but it may also be secondary to disorders such as myeloproliferativediseases. Although a wide variety of therapies have been tried,no effective treatment is yet available.
A 28-year-old woman presented with severe, persistent burningpain in the legs and feet, with marked erythema, swelling, andwarmth (Figure 1, left-hand panels). The erythema had begunat the age of four years, with no associated disorder. Afteradolescence, the symptoms became . . . [Full Text of this Article]
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