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Volume 349:829-830 August 28, 2003 Number 9
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Cardiac-Allograft Vasculopathy
Robin K. Avery, M.D.

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-Related Article
 by Eisen, H. J.
-PubMed Citation
Vasculopathy of cardiac allografts is a major therapeutic challenge, occurring in 50 percent or more of heart-transplant recipients in the first several years after surgery. Improving survival for these patients will require the use of new strategies to prevent this relentlessly progressive complication. Allograft vasculopathy involves diffuse narrowing and occlusion of the coronary arteries, rather than the more focal lesions of conventional atherosclerosis (see Figure).1 The addition of intravascular ultrasonography to standard coronary angiography increases the sensitivity of the procedure for diagnosis and provides a concentric view of the vessel under study.

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Typical Atherosclerosis and Allograft Vasculopathy.

The typical . . . [Full Text of this Article]

 

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From the Department of Infectious Disease and Transplant Center, Cleveland Clinic Foundation, Cleveland.


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