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Volume 350:88-89 January 1, 2004 Number 1
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Multifocal Myoclonus Induced by Trimethoprim–Sulfamethoxazole Therapy in a Patient with Nocardia Infection

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To the Editor: A 63-year-old woman with a history of non-Hodgkin's lymphoma that had been treated 25 years previously, as well as a history of hypertension, hypercholesterolemia, transient ischemic attack, and acute myelogenous leukemia with induction of remission three months previously, was admitted to our hospital with a five-day history of fever, fatigue, decreased appetite, and leukocytosis (white-cell count, 18,000 per cubic millimeter), without evidence of a recurrence of leukemia. Blood cultures grew Nocardia asteroides. The patient had no skin lesions or new focal neurologic signs. A computed tomographic scan of the chest revealed multiple new bilateral nodules. The . . . [Full Text of this Article]


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