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Volume 350:963-965 March 4, 2004 Number 10 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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GB virus C (GBV-C), an RNA virus in the Flaviviridae family, is a close relative of the hepatitis C virus. Although it has been shown that many people worldwide are infected with this virus, no clear association between the virus and a known disease state has been demonstrated. GBV-C has been shown to replicate in human peripheral-blood mononuclear cells in vitro, and it commonly coinfects patients with human immunodeficiency virus (HIV). GBV-C is transmitted through predominantly parenteral routes and has a high seroprevalence among intravenous-drug users. Nonetheless, the sexual transmission of GBV-C has also been demonstrated recently. Infection with or . . . [Full Text of this Article]

Source Information

From the Center for Human Virology and Biodefense, Division of Infectious Diseases and Environmental Medicine, Thomas Jefferson University, Philadelphia.

This article has been cited by other articles:

• Xiang, J., McLinden, J. H., Chang, Q., Kaufman, T. M., Stapleton, J. T. (2006). An 85-aa segment of the GB virus type C NS5A phosphoprotein inhibits HIV-1 replication in CD4+ Jurkat T cells. Proc. Natl. Acad. Sci. USA 103: 15570-15575 [Abstract] [Full Text]