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Volume 350:1150-1152 March 11, 2004 Number 11
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Lp(a) Lipoprotein, Vascular Disease, and Mortality in the Elderly

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by Ariyo, A. A.
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To the Editor: Ariyo et al. (Nov. 27 issue)1 show that Lp(a) lipoprotein is an important risk factor for stroke and death in elderly men. However, Lp(a) lipoprotein did not prove to be predictive of coronary artery disease, which is surprising for an atherosclerotic and prothrombotic risk factor. One explanation may be that patients with established coronary heart disease were excluded from the study.

We have used the opposite approach by including only patients with angiographically proven coronary artery disease. In our series of 451 nondiabetic patients, Lp(a) lipoprotein proved to be independently predictive of overall death as well as . . . [Full Text of this Article]



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