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Correspondence
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Volume 350:1157-1159 March 11, 2004 Number 11
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Myopathy in Children Receiving High-Dose Inhaled Fluticasone

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To the Editor: Inhaled corticosteroids are primary controllers of asthma, and they are safe if used in moderate doses.1 Myopathy is a known side effect of oral corticosteroid therapy,2 but it has so far not been linked to the use of inhaled corticosteroids in children. Fluticasone propionate is a potent inhaled corticosteroid that has been associated with adrenocortical insufficiency if given in high doses (>400 µg per day).3

A girl, 7.9 years old, was referred for evaluation because of fatigue leading to her withdrawal from competitive ice-skating, then to half-time absence from school, and ultimately to her requiring a wheelchair . . . [Full Text of this Article]




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