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A 34-year-old woman was admitted for acute right hemiparesis, which resolved within 24 hours. She had no history of hypertension, diabetes, migraine, or smoking. Since early childhood, she had had widespread cutaneous, mottled-purple discoloration on her face (Panel A) and other parts of her body, which had been diagnosed as systemic angiomatosis. The result of a test for antiphospholipid antibodies was positive (47.4 IgG phospholipid units per milliliter [normal range, <20]). T2-weighted magnetic resonance images revealed multiple periventricular lesions within the white matter of the brain (Panel B). Examination of a skin-biopsy specimen showed a thickened vessel wall with . . . [Full Text of this Article] |
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