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Images in Clinical Medicine
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Volume 350:1338 March 25, 2004 Number 13
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Pemberton's Sign

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A 58-year-old woman with a 20-year history of goiter presented with a two-month history of progressive dyspnea on exertion, occasional stridor, and a choking sensation while supine. She had previously been asymptomatic. Physical examination revealed a diffusely enlarged thyroid with no palpable nodules (Panel A), but the lower poles of the thyroid were not palpable. Within 30 seconds after she raised both arms simultaneously (Pemberton's maneuver), marked facial plethora (Pemberton's sign) developed, indicating compression of the jugular veins (Panel B). The patient's serum thyrotropin and free thyroxine concentrations were normal. Computed tomography of the neck revealed a large goiter extending . . . [Full Text of this Article]

 

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Pemberton's Sign
Pearce E. N., Braverman L. E., Basaria S., Salvatori R.
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N Engl J Med 2004; 351:196, Jul 8, 2004. Correspondence

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