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Previous Volume 350:1349-1351 March 25, 2004 Number 13 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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Physicians caring for pregnant women and their preterm infants have used corticosteroids since Liggins and Howie reported in 1972 that prenatal betamethasone decreased the incidence of the respiratory distress syndrome and increased the survival of preterm infants.¹ This infatuation with corticosteroids is not unique to perinatal medicine; corticosteroids have been used for almost every human disease for which there is no effective therapy. Despite an astounding number of randomized, controlled trials of corticosteroids in perinatal medicine, we remain uncertain about their appropriate use. The Cochrane Review of 18 trials of prenatal corticosteroids demonstrated compelling benefits for infants delivered before 32 . . . [Full Text of this Article]

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From the Division of Pulmonary Biology and Neonatology, Cincinnati Children's Hospital Medical Center, Cincinnati.

Related Letters:

Postnatal Dexamethasone for Lung Disease of Prematurity
Lommatzsch M., Klotz J., Virchow J. C. Jr., Watchko J. F., Brozanski B. S., Gordon P. V., Yeh T. F., Lin H. C., Huang C. C., Jobe A. H.
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N Engl J Med 2004; 350:2715-2718, Jun 24, 2004. Correspondence

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