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Correspondence
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Volume 350:1359-1361 March 25, 2004 Number 13
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Finasteride in Benign Prostatic Hyperplasia

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 by McConnell, J. D.
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To the Editor: In the United States, the incidence of breast cancer in men 65 years of age or older is 5.5 cases per 100,000 man-years.1 The finding, reported by McConnell et al. (Dec. 18 issue),2 that four men had breast cancer after treatment with finasteride alone or finasteride with doxazosin in a trial of the size and duration of the Medical Therapy of Prostatic Symptoms (MTOPS) study is unexpected.

From 1992 through December 2003, the Food and Drug Administration (FDA) received reports of 13 men in the United States in whom breast cancer developed during finasteride therapy (9 men) . . . [Full Text of this Article]


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