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Editorial
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Volume 350:1450-1452 April 1, 2004 Number 14
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C-Reactive Protein Reassessed
Alan R. Tall, M.B., B.S.

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 by Danesh, J.
-PubMed Citation
In this issue of the Journal, Danesh and colleagues report that elevated levels of C-reactive protein (CRP) are associated with only a moderate increase in the risk of coronary heart disease (CHD).1 Although these findings are in line with those of other large studies, the independent relative risk associated with increased CRP levels is considerably less than in some earlier reports. Using a multivariate analysis, the authors found that the predictive value of CRP measurement adds relatively little to that provided by assessments of traditional risk factors. In contrast, a smaller study suggested that the CRP level could be more . . . [Full Text of this Article]


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From the Division of Molecular Medicine, Department of Medicine, Columbia University Medical Center, New York.


Related Letters:

C-Reactive Protein and Coronary Heart Disease
Glynn R. J., Cook N. R., Libby P., Willerson J. T., Braunwald E., Foody J. M., Gotto A. M., Wenger N., Ridker P. M., Koenig W., Fuster V., Danesh J., Pepys M., Gudnason V.
Extract | Full Text | PDF  
N Engl J Med 2004; 351:295-298, Jul 15, 2004. Correspondence

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