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Previous Volume 350:1526-1534 April 8, 2004 Number 15 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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This Journal feature begins with a case vignette highlighting a common clinical problem. Evidence supporting various strategies is then presented, followed by a review of formal guidelines, when they exist. The article ends with the author's clinical recommendations.

A 45-year-old fair-skinned woman has noted increasing sallowness, roughness, fine wrinkles, and mottled hyperpigmentation on her face. She is bothered by these changes and is worried about the development of nonmelanoma skin cancer. What treatments may minimize skin aging and lower the risk of skin cancer?

The Clinical Problem

Aging and exposure to the environment affect facial appearance. Age-related changes include benign growths and "gravitation," . . . [Full Text of this Article]

Strategies and Evidence

Assessment

Prevention and Therapy

            Protection from the Sun

            Hydroxy Acids

            Topical Retinoids

            Fluorouracil Cream

Procedures for Facial Rejuvenation

            Botulinum Toxin

            Skin Fillers

            Simple Office Procedures

Areas of Uncertainty

Guidelines

Conclusions and Recommendations

Source Information

From the Department of Dermatology, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston.

Address reprint requests to Dr. Stern at the Department of Dermatology, Beth Israel Deaconess Medical Center, 330 Brookline Ave., Boston, MA 02215, or at rstern@bidmc.harvard.edu.

Related Letters:

Treatment of Photoaging
Rohrich R. J., Decherd M. E., Stern R. S.
Extract | Full Text | PDF  
N Engl J Med 2004; 351:614-615, Aug 5, 2004. Correspondence

This article has been cited by other articles:

• FOTIOU, S., FOTIOU, D., DELICONSTANTINOS, G. (2009). Formation of Heme-iron Complexes with Nitric Oxide (NO) and Peroxynitrite (ONOO-) after Ultraviolet Radiation as a Protective Mechanism in Rat Skin. In Vivo 23: 281-286 [Abstract] [Full Text]  
• Green, A. C., Williams, G. M. (2007). Point: Sunscreen Use Is a Safe and Effective Approach to Skin Cancer Prevention. Cancer Epidemiol. Biomarkers Prev. 16: 1921-1922 [Full Text]  
• Rohrich, R. J., Decherd, M. E., Stern, R. S. (2004). Treatment of Photoaging. NEJM 351: 614-615 [Full Text]