FREE NEJM E-TOC    HOME   |   SUBSCRIBE   |   CURRENT ISSUE   |   PAST ISSUES   |   COLLECTIONS   |   Search Term  Advanced Search

Sign in | Get NEJM's E-Mail Table of Contents — Free | Subscribe

Previous Volume 350:1930-1931 May 6, 2004 Number 19 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

	Full Text PDF PDA Full Text Purchase this article Letters Add to Personal Archive Add to Citation Manager Notify a Friend E-mail When Cited E-mail When Letters Appear Related Article by Zile, M. R. PubMed Citation

Heart failure is common and costly, and it primarily affects the elderly. As the elderly population expands, there will be marked increases in the number of persons with heart failure. Epidemiologic studies have established that 40 percent to 50 percent of patients with heart failure have a normal ejection fraction (50 percent) without primary valve disease, a clinical syndrome that is commonly referred to as "diastolic" heart failure. Despite great progress in our understanding of and therapeutic approach to heart failure associated with systolic dysfunction, or systolic heart failure, we are now realizing that basic research and clinical investigations . . . [Full Text of this Article]

Source Information

From the Mayo Heart Failure Program and Mayo Cardiorenal Research Laboratory, Cardiovascular Division, Department of Internal Medicine, Mayo Clinic College of Medicine, Rochester, Minn.

Related Letters:

Diastolic Heart Failure
Maurer M. S., Packer M., Burkhoff D., King D. L., Grieff M., Zile M. R., Baicu C. F., Gaasch W. H., Redfield M. M.
Extract | Full Text | PDF  
N Engl J Med 2004; 351:1143-1145, Sep 9, 2004. Correspondence

This article has been cited by other articles:

• Davis, B. R., Kostis, J. B., Simpson, L. M., Black, H. R., Cushman, W. C., Einhorn, P. T., Farber, M. A., Ford, C. E., Levy, D., Massie, B. M., Nawaz, S., for the ALLHAT Collaborative Research Group, (2008). Heart Failure With Preserved and Reduced Left Ventricular Ejection Fraction in the Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial. Circulation 118: 2259-2267 [Abstract] [Full Text]  
• Rich, S., Rabinovitch, M. (2008). Diagnosis and Treatment of Secondary (Non-Category 1) Pulmonary Hypertension. Circulation 118: 2190-2199 [Full Text]  
• LaCroix, C., Freeling, J., Giles, A., Wess, J., Li, Y.-F. (2008). Deficiency of M2 muscarinic acetylcholine receptors increases susceptibility of ventricular function to chronic adrenergic stress. Am. J. Physiol. Heart Circ. Physiol. 294: H810-H820 [Abstract] [Full Text]  
• Dandapantula, H. K., Afonso, L., Katkuri, H., Chandu, L., Spears, J. R., Shapiro, B. P., McGoon, M. M., Redfield, M. M. (2007). Unexplained Pulmonary Hypertension in Elderly Patients: Role of Heart Failure With Normal Ejection Fraction, Bernheim Effect, and Reverse Bernheim Effect. Chest 131: 1987-1988 [Full Text]  
• Nishimura, R. A., Jaber, W. (2007). Understanding "Diastolic Heart Failure": The Tip of the Iceberg. J Am Coll Cardiol 49: 695-697 [Full Text]  
• van Heerebeek, L., Borbely, A., Niessen, H. W.M., Bronzwaer, J. G.F., van der Velden, J., Stienen, G. J.M., Linke, W. A., Laarman, G. J., Paulus, W. J. (2006). Myocardial Structure and Function Differ in Systolic and Diastolic Heart Failure. Circulation 113: 1966-1973 [Abstract] [Full Text]  
• Riordan, M. M., Kovacs, S. J. (2006). Quantitation of mitral annular oscillations and longitudinal "ringing" of the left ventricle: a new window into longitudinal diastolic function. J. Appl. Physiol. 100: 112-119 [Abstract] [Full Text]  
• Fukuta, H., Sane, D. C., Brucks, S., Little, W. C. (2005). Statin Therapy May Be Associated With Lower Mortality in Patients With Diastolic Heart Failure: A Preliminary Report. Circulation 112: 357-363 [Abstract] [Full Text]  
• Borbely, A., van der Velden, J., Papp, Z., Bronzwaer, J. G.F., Edes, I., Stienen, G. J.M., Paulus, W. J. (2005). Cardiomyocyte Stiffness in Diastolic Heart Failure. Circulation 111: 774-781 [Abstract] [Full Text]  
• Maurer, M. S., Spevack, D., Burkhoff, D., Kronzon, I. (2004). Diastolic dysfunction: Can it be diagnosed by Doppler echocardiography?. J Am Coll Cardiol 44: 1543-1549 [Abstract] [Full Text]  
• Maurer, M. S., Packer, M., Burkhoff, D., King, D. L., Grieff, M., Zile, M. R., Baicu, C. F., Gaasch, W. H., Redfield, M. M. (2004). Diastolic Heart Failure. NEJM 351: 1143-1145 [Full Text]