Squamous-cell cancer of the head and neck is the sixth mostcommon cancer worldwide, with a lifetime risk of 2 percent formen and 0.6 percent for women. There are approximately 76,000and 37,000 new cases of oral-cavity, pharyngeal, and laryngalcancer diagnosed each year in Western Europe and the UnitedStates, respectively. The presence or absence of local and regionaldisease primarily determines the treatment outcome among thesepatients. Nonetheless, although the incidence of distant metastasesis relatively low, as compared with that of other cancers ofthe upper aerodigestive tract, distant metastases will developin almost one third . . . [Full Text of this Article]
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From the Academic Department of Oncology, University College London, London (M.I.S.), and the Marie Curie Research Wing, Mount Vernon Hospital, Northwood, Middlesex, United Kingdom (M.I.S., A.R.).
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