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A 75-year-old man with idiopathic pulmonary fibrosis was admitted because of progressive shortness of breath. He stated that he had not had new cough, fever, chest pain, palpitations, orthopnea, or paroxysmal nocturnal dyspnea. His home oxygen requirement had increased from 3 liters per minute to 6 liters per minute, administered by nasal cannula. The patient had received the diagnosis of idiopathic pulmonary fibrosis in 1998 on the basis of clinical and radiographic findings (Panel A). His disease had progressed despite corticosteroid and interferon gamma therapy. Repeated computed tomography showed marked progression of fibrotic changes (Panel B). Broad areas of honeycomb . . . [Full Text of this Article] |
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