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A 49-year-old left-handed woman was evaluated in the neurology clinic because of painful asymmetric neuropathy.
The patient had been well until several years earlier, when numbness developed in the right hand. A right carpal-tunnelrelease operation had been performed eight months before the current evaluation, but without benefit. During the four months before the evaluation, she experienced increasing burning pain in the same hand, and similar symptoms developed in the left hand. She frequently observed blisters on the first, second, and third digits of the right hand, without any recollection of injury. She had decreased sensation in the legs, particularly a
Differential Diagnosis
Characterizing a Peripheral Neuropathy
The Process of Differential Diagnosis
Narrowing the Differential Diagnosis
Clinical Diagnosis
Dr. David A. Chad's Diagnosis
Pathological Discussion
Anatomical Diagnosis
Addendum
Source Information
From the Department of Neurology, UMass Memorial Health Care, and the Departments of Neurology and Pathology, University of Massachusetts Medical School, Worcester (D.A.C.); and the Department of Pathology, Division of Neuropathology, Massachusetts General Hospital, and the Department of Pathology, Harvard Medical School (E.T.H.-W.).
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