Idiopathic pulmonary fibrosis, defined pathologically as usualinterstitial pneumonia, is a fatal disease that occurs mostcommonly among persons who are 60 years of age or older andin otherwise good health. Usual interstitial pneumonia progressivelyimpairs breathing, but because its onset is insidious, patientsare frequently treated for other diseases for many months. Bythe time the diagnosis is established, pulmonary function hasoften substantially deteriorated.1
Several entities fall under the wide umbrella of chronic interstitialpneumonias,2 including usual interstitial pneumonia, nonspecificinterstitial pneumonitis, desquamative interstitial pneumonia,acute interstitial pneumonia, respiratory bronchiolitisassociatedinterstitial lung disease, and cryptogenic organizing pneumonia.3. . . [Full Text of this Article]
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From the Division of Pulmonary and Critical Care Medicine, Mount Sinai Medical Center, New York.
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Interferon Gamma-1b for Pulmonary Fibrosis
Hill A. R., Fruchter O., Eisner M. D., Tsoutsou P. G., Gourgoulianis K. I., Vourlekis J. S., Richeldi L., Raghu G., King T. E. Jr., Teirstein A. S.
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N Engl J Med 2004;
350:1794-1797, Apr 22, 2004.
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