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Volume 350:2422-2423 June 3, 2004 Number 23
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Acute Renal Colic

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by Teichman, J. M.H.
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To the Editor: Although generally comprehensive, Teichman's review of acute renal colic due to ureteral calculus (Feb. 12 issue)1 failed to mention the calcium-channel blocker nifedipine in the medical treatment of patients with ureteral colic. Three randomized, controlled trials have demonstrated the favorable effects of a combination of nifedipine, corticosteroids, and nonsteroidal antiinflammatory drugs (NSAIDs) on several clinically meaningful end points, including spontaneous stone expulsion, time to stone passage, and requirements for pain medication. These studies showed up to twofold improvements in rates of spontaneous stone passage and greater than 50 percent reductions in the time required to achieve this . . . [Full Text of this Article]



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