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Clinical Practice
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Volume 350:259-265 January 15, 2004 Number 3
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Obsessive–Compulsive Disorder
Michael A. Jenike, M.D.

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This Journal feature begins with a case vignette highlighting a common clinical problem. Evidence supporting various strategies is then presented, followed by a review of formal guidelines, when they exist. The article ends with the author's clinical recommendations.

A 33-year-old woman presents with a seven-year history of hand washing for two to six hours a day, as well as urges to check doors and stoves extensively before leaving her home. Her life is restricted, and her family members are upset about her behavior. How should she be evaluated and treated?

The Clinical Problem

This vignette describes a typical patient with an anxiety disorder . . . [Full Text of this Article]

Strategies and Evidence

Diagnosis

Treatment

            Cognitive–Behavioral Therapy

Initial Drug Treatment

            Augmentation of Serotonin-Reuptake–Inhibitor Therapy and Trials of Alternative Drugs

            Neurosurgery

Areas of Uncertainty

Guidelines

Conclusions and Recommendations


Source Information

From the Department of Psychiatry, Massachusetts General Hospital, Boston; McLean Hospital, Belmont, Mass.; and Harvard Medical School, Boston.

Address reprint requests to Dr. Jenike at jenike@comcast.net.


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