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Previous Volume 350:515-516 January 29, 2004 Number 5 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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To the Editor: Nathan and Wilson (Nov. 6 issue)¹ discuss the position of the National Institutes of Health (NIH) with respect to clinical research. The NIH is biased toward basic science and is prejudiced by the idea that clinical research is best performed in a university setting by means of prospective trials. However, many clinical questions cannot be addressed in this way, especially when the goal is to determine which established techniques are most effective in an era of cost containment. Doctors with access to the numbers of patients needed for both retrospective and prospective studies of outcomes are frequently . . . [Full Text of this Article]

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