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Correspondence
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Volume 350:622 February 5, 2004 Number 6
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Effects of Estrogen plus Progestin on Health-Related Quality of Life

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 by Hays, J.
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To the Editor: Hays et al. (May 8 issue)1 conclude that among postmenopausal women enrolled in the Women's Health Initiative (WHI) trial, use of an estrogen–progestin combination did not have a clinically meaningful effect on health-related quality of life, except for a benefit with regard to sleep disturbances among women 50 to 54 years old who had moderate-to-severe vasomotor symptoms. However, the estrogen–progestin combination was associated with significant improvements in the severity of hot flashes and night sweats among women with moderate-to-severe vasomotor symptoms. These findings are clinically relevant and may be used by physicians and menopausal women to guide . . . [Full Text of this Article]


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