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Volume 350:624 February 5, 2004 Number 6
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Tissue Matching before the Era of HLA Typing

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by van Rood, J. J.
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To the Editor: In the summer of 1961, I "volunteered" for $50 to receive skin grafts in order to help determine the most suitable bone marrow donor for a teenage girl who was severely anemic as a result of treatment with chloramphenicol. I noted that the mother's graft was rejected in a manner similar to that of the patient's, whereas the brother's graft lasted several more days before rejection occurred and closely retained its larger size and shape (Figure 1). I was told that the girl did not live to receive a transplant. I have carried the scars . . . [Full Text of this Article]



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