Three to 5 percent of pregnancies in the United States are complicatedby preeclampsia, a multisystem disorder characterized by hypertensionand proteinuria that occurs after 20 weeks of pregnancy. Preeclampsiais associated with substantial risks. For the fetus, these includeintrauterine growth restriction, death, and prematurity withattendant complications, whereas the mother is at risk for seizures(eclampsia), renal failure, pulmonary edema, stroke, and death.Despite considerable research, the cause or causes of preeclampsiaremain unclear, and there are no clinically useful screeningtests to identify women in whom it will develop. Antihypertensivetherapy lowers maternal blood pressure but does . . . [Full Text of this Article]
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From the Division of Endocrinology, Diabetes, and Hypertension, Department of Medicine, Brigham and Women's Hospital, Boston (E.W.S).
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