To the Editor: Systemic mastocytosis is an uncommon and potentiallymisdiagnosed condition. Its hallmark is the accumulation andabnormal proliferation of mast cells in various tissues.
A two-month-old boy was referred to our facility with numerousbullae on the skin and unilateral periorbital cellulitis. Thechild was inconsolable, and his skin lesions, which had beenpresent since birth, progressed into subcutaneous nodules, plaques,and tumors, which were excoriated. He had hepatomegaly and wheezing.Findings on examination of biopsy specimens of the skin andbone marrow were consistent with the diagnosis of systemic mastocytosis.There were no bony lesions, and there . . . [Full Text of this Article]
Previous
