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Part of the differential diagnosis of a vesicular eruption must include smallpox. The characteristic smallpox lesions — papulovesicular pustules — develop two to four days after an influenza-like prodrome. The lesions progress from macules to papules to vesicular pustules. The eruption appears first on the face; spreads centrifugally to the scalp, upper chest, back, arms, and hands; and appears last on the abdomen, legs, and feet. The lesions are all in the same stage of development on a given area of the body.
The differential diagnosis of the vesicular-pustule stage includes varicella (chickenpox), eczema herpeticum (disseminated herpes), and herpes zoster. . . . [Full Text of this Article] |
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