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Previous Volume 350:823-825 February 19, 2004 Number 8 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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The incidence of malignant melanoma has been rising over the past three decades.¹ Much of the increase is accounted for by thin, localized cutaneous melanomas with the potential to be cured by surgery. Once melanoma spreads beyond the primary lesion, however, the likelihood of cure decreases dramatically. Five-year relative survival rates for patients with melanoma in the United States between 1992 and 1998 were 96 percent for those with local lesions but only 60 percent for patients whose melanomas had spread regionally and 14 percent for those with distant metastases.¹ The thickness of the tumor and the presence or absence . . . [Full Text of this Article]

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From the Clinical Immunology Service, Division of Hematologic Oncology, Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York.

Related Letters:

Excision Margins in High-Risk Malignant Melanoma
Hellman S., Hurt M. A., Thomas J. M., A'Hern R., Newton-Bishop J.
Extract | Full Text | PDF  
N Engl J Med 2004; 350:2305-2306, May 27, 2004. Correspondence

This article has been cited by other articles:

• Hellman, S., Hurt, M. A., Thomas, J. M., A'Hern, R., Newton-Bishop, J. (2004). Excision Margins in High-Risk Malignant Melanoma. NEJM 350: 2305-2306 [Full Text]  
• (2004). What Is the Optimal Excision Margin for Thick Melanomas?. JWatch General 2004: 6-6 [Full Text]