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(TNF-
)receptor fusion protein, has demonstrated efficacy in inflammatory bowel disease. In fact, in the most authoritative published experience with etanercept in the treatment of inflammatory bowel disease (a randomized, double-blind, placebo-controlled trial in patients with moderate-to-severe Crohn's disease), the drug was shown to be ineffective,2 and it does not have marketing approval for any indication in inflammatory bowel disease.
Suzanne B. Travers, M.D.
Centocor
Malvern, PA
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