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Book Review
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Volume 350:846 February 19, 2004 Number 8
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Dementia: Presentations, Differential Diagnosis, and Nosology

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Second edition. Edited by V. Olga B. Emery and Thomas E. Oxman. 533 pp. Baltimore, Johns Hopkins University Press, 2003. $99.95. ISBN 0-8018-7156-5.

The scope and content of this book are aptly indicated by the title. However, the order of the topics inverts the prevailing focus, which is nosology. Above all, this book critically examines the current state of the classification and diagnosis of dementia, espousing the concept that dementia syndromes are more accurately depicted as spectral composites than as singular, discrete clinicopathological entities. This overarching theme resonates with another emerging view of degenerative dementias that emphasizes the interacting components of pathologic processes that involve abnormal protein folding, abnormal accumulations of proteins, or both.

The first of the five parts of the book . . . [Full Text of this Article]




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