Readers could be forgiven for being confused by the literatureon micronutrients and the pathogenesis of human immunodeficiencyvirus (HIV) disease. Micronutrients play important roles inmaintaining immune function and neutralizing the reactive oxygenintermediates produced by activated macrophages and neutrophilsin their response to microorganisms. Serum and plasma measurementsof vitamins and trace elements, which are imperfect indicatorsof body stores, have shown that deficiencies are common amongHIV-infected persons, especially those who are underprivileged,such as women in developing countries, and injection-drug users.A vicious cycle has been envisaged in which undernourished HIV-infectedpersons have micronutrient deficiencies, leading . . . [Full Text of this Article]
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From the Centers for Disease Control and Prevention, Nairobi, Kenya.
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