The New England Journal of Medicine
e-mail icon  FREE NEJM E-TOC    HOME   |   SUBSCRIBE   |   CURRENT ISSUE   |   PAST ISSUES   |   COLLECTIONS   |    Advanced Search
Sign in | Get NEJM's E-Mail Table of Contents — Free | Subscribe
 
Correspondence
PreviousPrevious
Volume 351:1032-1033 September 2, 2004 Number 10
NextNext

Hypoparathyroidism and Autoimmune Polyendocrine Syndromes

Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

 Sign up for free e-toc
 

This Article
-Full Text
- PDF
-PDA Full Text
-Purchase this article

Tools and Services
-Add to Personal Archive
-Add to Citation Manager
-Notify a Friend
-E-mail When Cited
-E-mail When Letters Appear

More Information
-Related Article
by Eisenbarth, G. S.
-PubMed Citation
To the Editor: In their review of autoimmune polyendocrine syndromes, Eisenbarth and Gottlieb (May 13 issue)1 do not, in our view, sufficiently discuss autoimmune hypoparathyroidism and recent advances in its understanding. Autoimmune hypoparathyroidism is present in 80 to 85 percent of patients with autoimmune polyendocrine syndrome type I and up to 5 percent of patients with autoimmune polyendocrine syndrome type II. The autoantigens were unknown until the extracellular domain of the calcium-sensing receptor was identified as a potential target.2 The calcium-sensing receptor is a cell-surface, G protein–coupled receptor through which parathyroid cells, thyroidal C cells, and various kidney cells recognize . . . [Full Text of this Article]



HOME  |  SUBSCRIBE  |  SEARCH  |  CURRENT ISSUE  |  PAST ISSUES  |  COLLECTIONS  |  PRIVACY  |  TERMS OF USE  |  HELP  |  beta.nejm.org

Comments and questions? Please contact us.

The New England Journal of Medicine is owned, published, and copyrighted © 2009 Massachusetts Medical Society. All rights reserved.