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Case Records of the Massachusetts General Hospital
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Volume 351:1333-1341 September 23, 2004 Number 13
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Case 30-2004 — A 37-Year-Old Woman with Paresthesias of the Arms and Legs
Peter W. Marks, M.D., Ph.D., and Lawrence R. Zukerberg, M.D.

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Presentation of Case

A 37-year-old woman was seen in the clinic because of numbness in the arms and legs.

Four months earlier, she had noticed tingling and numbness in the fingertips, without weakness, three weeks after having last ridden a bicycle. She consulted her primary care physician. The temperature was 37.2°C and the blood pressure 115/85 mm Hg. The height was 1.75 m and the weight 69.1 kg. The lungs were clear to auscultation, and the heart sounds were normal. No rash or lymphadenopathy was found. Examination of the breasts, abdomen, and arms and legs and a pelvic examination revealed no abnormalities. The . . . [Full Text of this Article]

Differential Diagnosis

Paresthesias

Macrocytic Anemia

Autoimmune Polyendocrine Syndrome

Pernicious Anemia

            Pathophysiological Features

            Diagnostic Testing

Clinical Diagnosis

Dr. Peter W. Marks's Diagnosis

Pathological Discussion

Discussion of Management

Anatomical Diagnosis


Source Information

From the Department of Medicine, Division of Hematology, Brigham and Women's Hospital (P.W.M.); the Departments of Medicine (P.W.M.) and Pathology (L.R.Z.), Harvard Medical School; and the Department of Pathology, Massachusetts General Hospital (L.R.Z.) — all in Boston.


Related Letters:

Case 30-2004: A Woman with Paresthesias
Davies S. V., Marks P. W.
Extract | Full Text | PDF  
N Engl J Med 2005; 352:419-420, Jan 27, 2005. Correspondence

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