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Correspondence
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Volume 351:1354-1357 September 23, 2004 Number 13
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Metabolic Effects of Liposuction — Yes or No?

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 by Klein, S.
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To the Editor: Klein and colleagues (June 17 issue)1 report an absence of effects of abdominal liposuction on cardiovascular risk factors, inflammatory markers, and insulin resistance in obese women. We would suggest alternative explanations for their negative findings. The small number of subjects investigated (eight obese women without diabetes) and the limited length of follow-up (10 to 12 weeks) precluded the emergence of significant differences. We pooled data from our own studies2,3,4 evaluating the effect of large-volume liposuction on markers of vascular inflammation and insulin resistance in 45 premenopausal obese women (mean [±SD] age, 37±4 years) who were followed for . . . [Full Text of this Article]


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