Westernized countries are in the midst of an asthma epidemic.Despite much effort, therapeutic advances have not kept pacewith the dramatic increases in the incidence, prevalence, andseverity of allergic asthma that have occurred over the pasttwo decades in such countries. A recent study by Zhu et al.provides new and unexpected insight into the pathogenesis ofallergic asthma that could fuel the development of new therapies.1
Allergic asthma is thought to result from maladaptive inflammatoryresponses to ubiquitous environmental proteins in geneticallysusceptible persons. More specifically, allergic asthma is achronic inflammatory disorder of the airways mediated . . . [Full Text of this Article]
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From the Divisions of Immunobiology and Molecular Immunology, Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati.
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