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Volume 351:1461-1463 September 30, 2004 Number 14
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Management of Chronic Obstructive Pulmonary Disease

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by Sutherland, E. R.
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To the Editor: In their comprehensive review article on the management of chronic obstructive pulmonary disease (COPD) (June 24 issue),1 Sutherland and Cherniack discuss noninvasive ventilation as a means of improving hypercapnia and increasing the quality of life in patients with COPD. In contrast, in a recent randomized trial of the use of noninvasive ventilation in patients in whom respiratory failure developed after extubation, mortality was almost twice as high among patients treated with noninvasive ventilation as among patients receiving standard medical therapy.2 In addition, there was no difference in the rate of reintubation between the groups. This study suggests . . . [Full Text of this Article]



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