
View larger version (70K):
[in this window]
[in a new window]
|
A 56-year-old woman, who was a pediatric surgeon, presented with a five-year history of memory deficits, loss of professional self-confidence, and dysphoric mood that was unresponsive to antidepressant medication; her symptoms had necessitated early retirement. Notable findings on the physical examination included a large head circumference (59 cm) and a bulging forehead. Neurologic examination showed bilateral palmomental reflexes but no other frontal reflexes. The patient was not incontinent and had a normal gait.
T1-weighted magnetic resonance imaging (MRI) showed gross enlargement of the lateral, third, and fourth ventricles and effacement of the subarachnoid space (Panels A and B). No . . . [Full Text of this Article] |