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Previous Volume 351:1679-1681 October 14, 2004 Number 16 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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Despite improved treatment, mortality rates from breast cancer remain high, partly because of the increasing incidence of the disease. Understanding the causes of breast cancer could ultimately lead to its prevention. Many observations point to early life as a susceptible period in mammary carcinogenesis. Early menarche, late first delivery, and ionizing radiation during early life are documented risk factors. High stature, which to a certain extent is determined by childhood nutrition, has consistently been associated with an increase in the risk of breast cancer.¹

Studies in animals also indicate that the mammary gland is most vulnerable to carcinogenic influences before . . . [Full Text of this Article]

Source Information

From the Obstetrics and Gynecology Epidemiology Center (K.B.M.) and the Channing Laboratory (K.B.M., W.C.W.), Brigham and Women's Hospital, Harvard Medical School; and the Departments of Epidemiology (K.B.M., W.C.W.) and Nutrition (W.C.W.), Harvard School of Public Health — all in Boston.

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