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Editorial
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Volume 351:1790-1792 October 21, 2004 Number 17
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Chemoradiotherapy for Rectal Cancer — When, Why, and How?
Robert D. Madoff, M.D.

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-Related Article
 by Sauer, R.
-PubMed Citation
Although colon cancer and rectal cancer share many features, clinicians should be aware of important differences in the clinical behavior and treatment of these two distinct diseases. Prominent among these is the tendency for rectal cancer — but not colon cancer — to recur locally. Local recurrence of rectal cancer is often catastrophic: it is difficult to cure, and the associated symptoms are debilitating. Accordingly, preventing local recurrence is one of the main goals of rectal-cancer treatment.

In 1990, a National Institutes of Health consensus conference recommended postoperative adjuvant chemoradiotherapy for patients with stage II rectal cancer (node-negative disease with . . . [Full Text of this Article]


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From the Division of Colon and Rectal Surgery, Department of Surgery, University of Minnesota, Minneapolis.


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