Syphilis Control -- A Continuing Challenge

doi:10.1056/NEJMp048126

GLOBAL HEALTH

Volume 351:122-124		July 8, 2004		Number 2

Syphilis Control — A Continuing Challenge

Edward W. Hook, III, M.D., and Rosanna W. Peeling, Ph.D.

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by Lukehart, S. A.

PubMed Citation

Syphilis. The name of this widespread and ancient disease isfamiliar to health care providers worldwide. This name recognition,however, belies the complexity of the disease, as well as thediagnostic and therapeutic challenges that continue to affectglobal efforts to control syphilis. Early (primary or secondary)syphilis is typically marked by ulcerative lesions that occurinitially at the site of inoculation, followed several monthslater by widespread cutaneous, mucosal, and even systemic manifestationsof the dissemination of the causal agent, Treponema pallidum(see Figure 1). Even without treatment, both primary and secondarylesions resolve, and the infection enters . . . [Full Text of this Article]

Source Information

From the Departments of Medicine, Microbiology, and Epidemiology, University of Alabama at Birmingham; and the Sexually Transmitted Disease Control Program, Jefferson County Department of Health — both in Birmingham, Ala. (E.W.H.); and Diagnostics Research and Development Program, UNICEF/UNDP/World Bank/WHO Special Program for Research and Training in Tropical Diseases, World Health Organization, Geneva (R.W.P.).