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A 72-year-old woman with a history of hematuria presented with a three-month history of weight loss and anorexia. Computed tomography (Panel A) and ultrasonography showed a solid mass infiltrating the renal pelvis of the nonfunctioning right kidney. The serum creatinine concentration was 1.1 mg per deciliter (97.2 µmol per liter), and cytologic examination of the urine revealed no abnormalities. Subsequent radical nephrectomy confirmed the presence of the mass at the upper pole and also revealed a complete staghorn pyelocaliceal and ureteral mass (Panel B). Histologic analysis showed that the lesion was a poorly differentiated renal-cell carcinoma (stage pT3aN0M0 according to . . . [Full Text of this Article] |