In this issue of the Journal, Taylor and colleagues report theresults of the African-American Heart Failure Trial (A-HeFT),a double-blind, randomized trial that evaluated the effect ofthe addition of isosorbide dinitrate and hydralazine to thebest conventional therapy in patients with symptomatic congestiveheart failure who identified themselves as black.1 The resultswith the combination therapy were markedly positive, meetingthe composite end point of the trial, which included death fromany cause, a first hospitalization for heart failure, and quality-of-lifemeasures. In addition, there was an impressive reduction inthe rate of death from any cause of . . . [Full Text of this Article]
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From the Department of Medicine, Cardiology Division, Johns Hopkins University School of Medicine, Baltimore.
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