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Previous Volume 351:2131-2133 November 11, 2004 Number 20 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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To the Editor: Vasan et al. and Dluhy and Williams (July 1 issue)^1,2 revisit the role of aldosterone in hypertension and suggest that the incidence of a positive relationship may be greater than previously thought. However, they do not consider the mechanism of aldosterone-induced hypertension. There are at least three possibilities. One is that an increase in blood volume acts directly to increase the blood pressure. This is not likely, because an intravenous infusion of saline has little immediate effect. The blood pressure will increase with time, however, which suggests an indirect mechanism, such as the release of a digitalis-like . . . [Full Text of this Article]

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