FREE NEJM E-TOC    HOME   |   SUBSCRIBE   |   CURRENT ISSUE   |   PAST ISSUES   |   COLLECTIONS   |   Search Term  Advanced Search

Sign in | Get NEJM's E-Mail Table of Contents — Free | Subscribe

Previous Volume 351:2333-2336 November 25, 2004 Number 22 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

	Full Text PDF PDA Full Text Purchase this article Letters Add to Personal Archive Add to Citation Manager Notify a Friend E-mail When Cited E-mail When Letters Appear Related Article by Stoler, J. M. PubMed Citation

For many observers, the term "genomic medicine" conjures up space-age images of microarray chips, bioinformatics, and designer drugs. Today, with medicine poised at the dawn of the genomic era, it is seductive to believe that such high-tech options have already become the most important genomic tools in health care. However, as so often happens in medicine, new developments do not eclipse the tried-and-true method; instead, they give it new meaning and power.

Most diseases are the result of the interactions of multiple genes and environmental factors. Although these interactions are complex, almost every patient today has access to a free, . . . [Full Text of this Article]

Overcoming the Obstacles

The Past as the Future

Source Information

From the National Human Genome Research Institute, National Institutes of Health, Bethesda, Md. (A.E.G., F.S.C.); and the Office of the Surgeon General, Department of Health and Human Services, Washington, D.C. (R.H.C.).

Address reprint requests to Dr. Guttmacher at Bldg. 31, Rm. 4B09, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD 20892-2152.

Related Letters:

Family History
Morita H., Nagai R., Gammenthaler S. A., Seltzer M. H., Guttmacher A. E., Collins F. S., Carmona R. H.
Extract | Full Text | PDF  
N Engl J Med 2005; 352:732-733, Feb 17, 2005. Correspondence

This article has been cited by other articles:

• Hampel, H., Frankel, W. L., Martin, E., Arnold, M., Khanduja, K., Kuebler, P., Clendenning, M., Sotamaa, K., Prior, T., Westman, J. A., Panescu, J., Fix, D., Lockman, J., LaJeunesse, J., Comeras, I., de la Chapelle, A. (2008). Feasibility of Screening for Lynch Syndrome Among Patients With Colorectal Cancer. JCO 26: 5783-5788 [Abstract] [Full Text]  
• Feero, W. G., Bigley, M. B., Brinner, K. M., The Family Health History Multi-Stakeholder Workgr, (2008). New Standards and Enhanced Utility for Family Health History Information in the Electronic Health Record: An Update from the American Health Information Community's Family Health History Multi-Stakeholder Workgroup. J. Am. Med. Inform. Assoc. 15: 723-728 [Abstract] [Full Text]  
• Khoury, M. J., Valdez, R., Albright, A. (2008). Public Health Genomics Approach to Type 2 Diabetes. Diabetes 57: 2911-2914 [Full Text]  
• Bonham, V. L. JD, Ramos, E. M. PhD MPH (2008). Unravelling the contributions of social, environmental and genetic factors to health differences. CMAJ 179: 629-630 [Full Text]  
• Wang, N.-Y., Young, J. H., Meoni, L. A., Ford, D. E., Erlinger, T. P., Klag, M. J. (2008). Blood Pressure Change and Risk of Hypertension Associated With Parental Hypertension: The Johns Hopkins Precursors Study. Arch Intern Med 168: 643-648 [Abstract] [Full Text]  
• Hemminki, K., Sundquist, J., Lorenzo Bermejo, J. (2008). Familial Risks for Cancer as the Basis for Evidence-Based Clinical Referral and Counseling. The Oncologist 13: 239-247 [Abstract] [Full Text]  
• Lynch, H. T., Lynch, J. F. (2008). Lynch Syndrome and the Role of the Registered Nurse: Commentary on "Hereditary Nonpolyposis Colorectal Cancer (Lynch Syndrome): Molecular Pathogenesis and Clinical Approaches to Diagnosis and Management for Nurses". Biol Res Nurs 9: 200-202  
• Hemminki, K., Sundquist, J., Bermejo, J. L. (2008). How common is familial cancer?. Ann Oncol 19: 163-167 [Abstract] [Full Text]  
• Valdez, R., Yoon, P. W., Liu, T., Khoury, M. J. (2007). Family History and Prevalence of Diabetes in the U.S. Population: The 6-year results from the National Health and Nutrition Examination Survey (1999 2004). Diabetes Care 30: 2517-2522 [Abstract] [Full Text]  
• Olney, R. S., Yoon, P. W. (2007). Role of Family Medical History Information in Pediatric Primary Care and Public Health: Introduction. Pediatrics 120: S57-S59 [Abstract] [Full Text]  
• Trotter, T. L., Martin, H. M. (2007). Family History in Pediatric Primary Care. Pediatrics 120: S60-S65 [Abstract] [Full Text]  
• Picchietti, D., Allen, R. P., Walters, A. S., Davidson, J. E., Myers, A., Ferini-Strambi, L. (2007). Restless Legs Syndrome: Prevalence and Impact in Children and Adolescents The Peds REST Study. Pediatrics 120: 253-266 [Abstract] [Full Text]  
• Simard, J., Dumont, M., Moisan, A.-M., Gaborieau, V., Vezina, H., Durocher, F., Chiquette, J., Plante, M., Avard, D., Bessette, P., Brousseau, C., Dorval, M., Godard, B., Houde, L., Joly, Y., Lajoie, M.-A., Leblanc, G., Lepine, J., Lesperance, B., Malouin, H., Parboosingh, J., Pichette, R., Provencher, L., Rheaume, J., Sinnett, D., Samson, C., Simard, J.-C., Tranchant, M., Voyer, P., INHERIT BRCAs, , Easton, D., Tavtigian, S. V, Knoppers, B.-M., Laframboise, R., Bridge, P., Goldgar, D. (2007). Evaluation of BRCA1 and BRCA2 mutation prevalence, risk prediction models and a multistep testing approach in French-Canadian families with high risk of breast and ovarian cancer. J. Med. Genet. 44: 107-121 [Abstract] [Full Text]  
• Gami, A. S., Rader, S., Svatikova, A., Wolk, R., Herold, D. L., Huyber, C., Winnicki, M., Somers, V. K. (2007). Familial Premature Coronary Artery Disease Mortality and Obstructive Sleep Apnea. Chest 131: 118-121 [Abstract] [Full Text]  
• Yeung, E. H., Pankow, J. S., Astor, B. C., Powe, N. R., Saudek, C. D., Kao, W.H. L. (2007). Increased Risk of Type 2 Diabetes From a Family History of Coronary Heart Disease and Type 2 Diabetes. Diabetes Care 30: 154-156 [Full Text]  
• Dekker, L. R.C., Bezzina, C. R., Henriques, J. P.S., Tanck, M. W., Koch, K. T., Alings, M. W., Arnold, A. E.R., de Boer, M.-J., Gorgels, A. P.M., Michels, H. R., Verkerk, A., Verheugt, F. W.A., Zijlstra, F., Wilde, A. A.M. (2006). Familial Sudden Death Is an Important Risk Factor for Primary Ventricular Fibrillation: A Case-Control Study in Acute Myocardial Infarction Patients. Circulation 114: 1140-1145 [Abstract] [Full Text]  
• Van Riper, M. (2006). Guest editorial: family nursing in the era of genomic health care: we should be doing so much more!. Journal of Family Nursing 12: 111-118  
• Frich, J. C., Ose, L., Malterud, K., Fugelli, P. (2006). Perceived Vulnerability to Heart Disease in Patients with Familial Hypercholesterolemia: A Qualitative Interview Study. Ann Fam Med 4: 198-204 [Abstract] [Full Text]  
• Murabito, J. M., Pencina, M. J., Nam, B.-H., D'Agostino, R. B. Sr, Wang, T. J., Lloyd-Jones, D., Wilson, P. W. F., O'Donnell, C. J. (2005). Sibling Cardiovascular Disease as a Risk Factor for Cardiovascular Disease in Middle-aged Adults. JAMA 294: 3117-3123 [Abstract] [Full Text]  
• Feetham, S. L. (2005). Family Nursing: Challenges and Opportunities: Providing Leadership in Family Nursing From Local to Global Health. Journal of Family Nursing 11: 327-331  
• Begg, C. B., Orlow, I., Hummer, A. J., Armstrong, B. K., Kricker, A., Marrett, L. D., Millikan, R. C., Gruber, S. B., Anton-Culver, H., Zanetti, R., Gallagher, R. P., Dwyer, T., Rebbeck, T. R., Mitra, N., Busam, K., From, L., Berwick, M., for the Genes Environment and Melanoma (GEM) Study, (2005). Lifetime Risk of Melanoma in CDKN2A Mutation Carriers in a Population-Based Sample. JNCI J Natl Cancer Inst 97: 1507-1515 [Abstract] [Full Text]  
• Peterson, S. K. (2005). The Role of the Family in Genetic Testing: Theoretical Perspectives, Current Knowledge, and Future Directions. Health Educ Behav 32: 627-639 [Abstract]  
• Burke, W. (2005). Contributions of Public Health to Genetics Education for Health Care Professionals. Health Educ Behav 32: 668-675 [Abstract]  
• Guttmacher, A. E., Collins, F. S. (2005). Realizing the Promise of Genomics in Biomedical Research. JAMA 294: 1399-1402 [Full Text]  
• Rubinstein, W. S., Roy, H. K. (2005). Practicing Medicine at the Front Lines of the Genomic Revolution. Arch Intern Med 165: 1815-1817 [Full Text]  
• Burke, W. (2005). Taking Family History Seriously. ANN INTERN MED 143: 388-389 [Full Text]  
• Hall, M., Olopade, O. I. (2005). Confronting Genetic Testing Disparities: Knowledge Is Power. JAMA 293: 1783-1785 [Full Text]  
• Morita, H., Nagai, R., Gammenthaler, S. A., Seltzer, M. H., Guttmacher, A. E., Collins, F. S., Carmona, R. H. (2005). Family History. NEJM 352: 732-733 [Full Text]