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Correspondence
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Volume 351:2349-2350 November 25, 2004 Number 22
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Medical Mystery — The Answer

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 by Wickless, S. C.
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To the Editor: The medical mystery in the October 7 issue1 involved a 16-year-old white boy who presented with generalized argyria after ingesting a silver-containing dietary supplement for approximately two years. The supplement was packaged so that it was identical to bottled water and was touted as a preventive for everyday infections. Pigmentary changes began on the boy's cheeks and progressed to involve his entire body within one year. Because of his graying complexion, a workup was performed for Addison's disease and cyanosis. All the results were negative or normal. There was no evidence of neuropathy or seizures.

A physical . . . [Full Text of this Article]




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