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Previous Volume 351:2454-2455 December 2, 2004 Number 23 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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To the Editor: Belmaker (July 29 issue)¹ reviews the syndrome of bipolar disorder. The lifetime prevalence of bipolar disorders among patients in primary care and general medical settings is considerably higher² than the approximately 1 percent consistently reported in the general population.³ Patients with bipolar disorder are much more likely to seek help when they are depressed, and a history of manic or hypomanic symptoms can be easily missed. There is a significant risk of psychiatric complications when an antidepressant drug is prescribed without concurrent use of a mood stabilizer, such as lithium, in a patient with bipolar disorder. Therefore, . . . [Full Text of this Article]

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