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Images in Clinical Medicine
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Volume 351:2740 December 23, 2004 Number 26
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Tacrolimus Ointment, Alcohol, and Facial Flushing

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A 56-year-old patient was treated with 0.1 percent tacrolimus ointment because of rosacea that had been aggravated by prolonged use of topical corticosteroids. After two weeks of treatment, she had an unprecedented episode of facial flushing during an evening reception where alcoholic beverages were served. The patient agreed to undergo a test to see whether the reaction could be reproduced in a clinical setting. After one week of twice-daily application of 0.5 g of 0.1 percent tacrolimus ointment on the face, she ingested 0.05 liter of white wine. The images show the patient before exposure to alcohol (Panel A) and . . . [Full Text of this Article]

 



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