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Previous Volume 351:2759-2760 December 23, 2004 Number 26 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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Humans are extraordinarily complex organisms; the intricacy of the underlying pattern of gene expression that orchestrates our development and governs our ability to respond to various stimuli is nothing short of marvelous. Every day of our lives, thousands upon thousands of genes are turned on or off, and the levels of messenger RNA (mRNA) expressed as a result of these genes increase or decrease in a coordinated and controlled manner. To orchestrate this complex series of molecular events, humans and other organisms have evolved sophisticated machinery that tightly regulates gene expression through a set of molecular switches — a challenge . . . [Full Text of this Article]

Source Information

From the Department of Surgery, Duke University Medical Center, Durham, N.C.

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